Synthesis of a derivative of ?-D-Glcp(1->2)-D-Galf suitable for further glycosylation and of ?-D-Glcp(1->2)-D-Gal, a disaccharide fragment obtained from varianose.

Shared by Brian Kiptoo • chemistry • 2012

This article is from Beilstein Journal of Organic Chemistry , volume 8 . Abstract The presence of galactofuranoyl units in infectious microorganisms has prompted the study of the metabolic pathways involved in their incorporation in glycans. Although much progress has been made with respect to the biosynthesis of β-D-Galf-containing glycoconjugates, the mechanisms by which α-D-Galf units are incorporated remain unclear. Penicillium varians is a non-pathogenic fungus that produces varianose, a polysaccharide containing both α- and β-D-Galf units, which can be used as a model for biosynthetic st